Phospholipids, Proteins and Platelet-Lipoid
نویسندگان
چکیده
منابع مشابه
Intraglomerular fibrin, platelet aggregation, and subendothelial deposits in lipoid nephrosis.
We have investigated the formation of fibrin, platelet aggregates, and subendothelial deposits in lipoid nephrosis. Fibrin formation was found in 10 cases of active lipoid nephrosis. Platelet aggregates were found in eight cases and subendothelial deposits in nine. Fibrin and platelets were also found in cases of nephrotic syndrome due to other causes, and in glomerulonephritis. Fibrin was gene...
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By JOHN H. FERGUSON, AARON J. MARCUS AND A. JEAN ROBINSON P LATELET PHOSPHATIDYLSERINE ( PS ) and phosphatidylethanolamine (PE) have been successfully isolated and purified1”8 by applying methods worked out by Rouser and colleagues4 for the corresponding brain phospholipids. With the modern evolution5t of clotting tests, applicable to research on the role of phosphatides7’8 in blood coagulation...
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Platelet phospholipids undergo significant alterations during aggregation induced by thrombin or other agents. There is an early increase in phosphatidic acid, with a decrease in phosphatidyl inositol. De novo synthesis of most phospholipids from 14C-glycerol is decreased. Thrombin stimulates 32P-phosphate incorporation into di- and triphosphoinositides, suggesting increased phosphorylation of ...
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The objective of this study was to follow the uptake and distribution of oleic and elaidic acids into human erythrocytes. platelets, and plasma phospholipids. The usc of dual and triple labeling methodology permitted a precise comparison of elaidic and oleic acid utilization. Elaidic acid (EI) was selectively concentrated in all th~ plasma phospholipids except for lysophosphatidylcholine. Three...
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The lipid composition of platelet cytoskeletons was analyzed. Triton X-100 (0.5%) was used to prepare cytoskeletons from thrombin-treated platelets. The lipid/protein ratio of platelet cytoskeletons was 0.260 and the phospholipid/protein ratio was 0.177, which were comparable to the ratios present in platelets. However, there was a selective enrichment of platelet lipids in platelet cytoskeleto...
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ژورنال
عنوان ژورنال: Nature
سال: 1958
ISSN: 0028-0836,1476-4687
DOI: 10.1038/181420a0